Multi- versus Single Injection Technique for Peripheral Nerve Blockaded: A Volunteer Study
- Conditions
- healthy volunteers
- Registration Number
- DRKS00003826
- Lead Sponsor
- Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakolgoie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 21
Healthy male volunteers aged between 18 and 45 years
-BMI < 30 kg/m2
-Written informed consent given by volunteers after being provided with detailed information about the nature, risks, and scope of the clinical study as well as the expected desirable and adverse effects of the drug
-No legal incapacity and/or other circumstances rendering the volunteer unable to understand the nature, scope and possible consequences of the study
-Anatomical abnormalities of the forearm identified by physical examination
-Use of NSAID during the last 2 weeks
-Known allergy or hypersensitivity against ropivacaine or other amino-amide LA
-Participation in another clinical study within the last 4 weeks prior to study
-Coagulopathy
-Abnormalities in ECG that are considered clinically relevant like AV-block or bradycardia
-Unreliability and/or lack of cooperation
-Other objections to participate in the study in the opinion of the investigator
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary endpoint is the sensory spread of the block. <br>Evaluation takes place with pin brick tests and will be evaluated after 2, 4, 6, 8, 10, 15, 20, 30, 60, 90,120,150, 180minutes until sensibility is completely recovered.<br>Complete blockade is achieved when VAS=3 within 20 minutes. <br>
- Secondary Outcome Measures
Name Time Method Onset time and duration of the block