Efficacy of Multiple Doses Intralesional Injection of Bevacizumab in Primary Pterygium Treatment

Phase 1

Recruiting

• Conditions: size of pterygiumsigns and symptoms of pterygiumside effects of intralesional injection of bevacizumab in primary pterygium; bevacizumab, pterygium, primary, treatment

• Registration Number: TCTR20180130003
• Lead Sponsor: Research Affairs, Faculty of Medicine, Khon Kaen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-30
• Study Completion: 2018-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

Primary pterygium patients older than 20 years

Exclusion Criteria

Ptergium involve visual axis, Recurrent pterygium, Pterygium with symblepharon, Patients with history of ocular chemical or thermal burn, Pregnant and breastfeeding female, Patients with history of stroke or thromboembolism disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Area of pterygium 0 wk, 4 wk, 24 wk mm square/ImageJ program

Secondary Outcome Measures

Name	Time	Method
symptoms(eye irritation, photophobia, epiphora, redness, amount of discharge, and blurred vision) 0 wk, 4 wk, 24 wk subjectively graded by the patients on an 11-point scale [range, 0 (low) to 10 (high)]