The effect of scaling on the concentrations of inflammatory factors in patients with gum diseases

Phase 2

• Conditions: chronic periodontitis.; Chronic periodontitis

• Registration Number: IRCT2016123131687N1
• Lead Sponsor: Vice chancellor for research,Dental faculty of Shahed university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

The inclusion criteria : presence of at least 20 teeth in the oral cavity; affliction with moderate and severe chronic periodontitis with radiographic evidence of bone loss
The exclusion criteria : patients with cardiovascular diseases and hypertension; use of tobacco; pathologic conditions in the oral cavity; subjects with chronic inflammatory conditions such as rheumatoid arthritis; presence of tumors; pregnancy; use of any medications affecting the periodontium; presence of systemic diseases that affect the course of periodontal disease; having undergone scaling and root planing during the previous 6 months; history of taking antibiotics and Nonsteroidal anti-inflammatory drug during the previous 3 months

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
S100A12. Timepoint: base line,4 weeks. Method of measurement: ELISA TEST.;IL22. Timepoint: base line,4 weeks. Method of measurement: ELISA TEST.

Secondary Outcome Measures

Name	Time	Method
Clinical attachment level. Timepoint: base line, 4 weeks. Method of measurement: by williams probe( clinical).;Clinical probing depth. Timepoint: base line , 4 weeks. Method of measurement: by williams probe ( clinical).