Comparison of 3 Novel Contact Lens Solutions on the Basal Lamina
Not Applicable
Completed
- Conditions
- Contact Lens Solution
- Registration Number
- NCT00691457
- Lead Sponsor
- Alcon Research
- Brief Summary
Three arm study comparing three novel contact lens solutions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change from baseline in corneal fluorescein staining as evaluated at Day 30 30 Days
- Secondary Outcome Measures
Name Time Method Confocal evaluation variables as measured at Days 0, 14, and 30 Day 0, 14, 30
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms do Opti-Free, ReNu Multiplus, and Clear Care contact lens solutions use to affect corneal basal lamina integrity?
How does the efficacy of NCT00691457's novel contact lens solutions compare to standard-of-care solutions like Sensitive or HydraGlyde in preserving corneal basement membrane structure?
Which corneal epithelial biomarkers correlate with response to Opti-Free, ReNu Multiplus, or Clear Care in patients with dry eye syndrome or contact lens-induced hypoxia?
What adverse events are associated with Alcon Research's novel contact lens solutions in NCT00691457, and how do they compare to traditional disinfecting agents like hydrogen peroxide-based systems?
Are there combination therapies or competitor formulations (e.g., Bausch & Lomb's Ultracare) that synergistically enhance basal lamina preservation when paired with these contact lens solutions?
Trial Locations
- Locations (1)
Virginia Beach, VA
🇺🇸Virginia Beach, Virginia, United States
Virginia Beach, VA🇺🇸Virginia Beach, Virginia, United States