Hemodynamic Effect of Prone Position in Non-intubated Patient With COVID 19

• Conditions: Pneumonia, Viral; Covid19
• Interventions: Procedure: prone position

• Registration Number: NCT04834947
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Prone position in non-intubated patient has shown some respiratory physiological benefits. Prone positioning in patient intubated with ARDS has shown hemodynamic benefits. We aim to compare hemodynamic assessment before and after prone positioning in non-intubated patient with COVID 19 pneumonia. The study hypothesis is that prone positioning in non-intubated patient improve right ventricular preload, reduce afterload and increase Cardiac index compared to supine position.

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Status Verified: 2021-03
• Study First Submitted: 2021-04-06
• Study First Submitted QC: 2021-04-06
• Last Update Submitted: 2021-04-06
• Study First Posted: 2021-04-08
• Last Update Posted: 2021-04-08
• Study Start: 2021-04-15
• Primary Completion: 2021-12-15
• Study Completion: 2021-12-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Adult patient
• COVID 19 pneumonias with Hypoxemia
• for whom prone positioning has been decided by the attending physician.

Read More

Exclusion Criteria

• Mechanical ventilation
• ECLS

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Prone position in non-intubated COVID19 , before and after.	prone position	Patients with non-intubated COVID19 pneumoniae for whom the clinician has decided to try prone positioning to increase the PaO2 in a context of hypoxemia with O2 requirement.

Primary Outcome Measures

Name	Time	Method
Hemodynamic effect	Cardiac index will be recorded before, just after prone position and after return to supine position.	Cardiac index

Trial Locations

Locations (1)

Service d'Anesthésie-Réanimation, Hôpital Louis Pradel,; 🇫🇷 Bron, France