Prone Position in Non-Invasive Ventilation and High-Flow Oxygen Therapy
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Evaluation of Prone Position Effect During NIV and HFNC on Acute Hypoxemic Respiratory Failure
- 发起方
- Hospital General Universitario Morales Meseguer
- 入组人数
- 100
- 主要终点
- Oro-tracheal entubation
- 最后更新
- 4年前
概览
简要总结
The aim of this trial is to study the effect of prone position during NIV and HFNC on acute hypoxemic respiratory patients.
详细描述
Inclusion Criteria: Adult patients with: • ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level) Exclusion Criteria * General NIV or HFNC contraindications * Immediate need for IOT * Prone position intolerance * Patients refusal to participate Interventions: * Prone position for 2-4 hours twice a day, for 3 days (first 3 days since admission to ICU) * Nurse surveilance: at least every 15 minutes Outcomes: * Need for IOT * Effects on the measurements specified above (particularly PaO2/FiO2)
研究者
Miguel Filipe Martins de Matos Navarro Guia
MD
Hospital General Universitario Morales Meseguer
入排标准
入选标准
- •Adult patients with:
- •ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level)
排除标准
- •General NIV or HFNC contraindications
- •Immediate need for IOT
- •Prone position intolerance
- •Patients refusal to participate
结局指标
主要结局
Oro-tracheal entubation
时间窗: 1 month
Oro-tracheal entubation avoidance
次要结局
- PaO2/FiO2(1 month)