Prone Position in Non-Invasive Ventilation and High-Flow Oxygen Therapy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Evaluation of Prone Position Effect During NIV and HFNC on Acute Hypoxemic Respiratory Failure
- Sponsor
- Hospital General Universitario Morales Meseguer
- Enrollment
- 100
- Primary Endpoint
- Oro-tracheal entubation
- Last Updated
- 4 years ago
Overview
Brief Summary
The aim of this trial is to study the effect of prone position during NIV and HFNC on acute hypoxemic respiratory patients.
Detailed Description
Inclusion Criteria: Adult patients with: • ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level) Exclusion Criteria * General NIV or HFNC contraindications * Immediate need for IOT * Prone position intolerance * Patients refusal to participate Interventions: * Prone position for 2-4 hours twice a day, for 3 days (first 3 days since admission to ICU) * Nurse surveilance: at least every 15 minutes Outcomes: * Need for IOT * Effects on the measurements specified above (particularly PaO2/FiO2)
Investigators
Miguel Filipe Martins de Matos Navarro Guia
MD
Hospital General Universitario Morales Meseguer
Eligibility Criteria
Inclusion Criteria
- •Adult patients with:
- •ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level)
Exclusion Criteria
- •General NIV or HFNC contraindications
- •Immediate need for IOT
- •Prone position intolerance
- •Patients refusal to participate
Outcomes
Primary Outcomes
Oro-tracheal entubation
Time Frame: 1 month
Oro-tracheal entubation avoidance
Secondary Outcomes
- PaO2/FiO2(1 month)