INternational observational study To Understand current practices for managing the respiratory support in critically ill patients

Not yet recruiting

• Conditions: Disorder of central nervous system, unspecified,

• Registration Number: CTRI/2019/01/017206
• Lead Sponsor: Non funded project

Brief Summary

Endotracheal intubation (ETI) in critically ill patients is a potentially life-threatening procedure and approximately one-third of ETIs is complicated by severe hypoxia, cardiovascular collapse and cardiac arrest. Critically ill are prone to severe complications as the consequence of the underlying acute respiratory failure or hemodynamic instability, reduced oxygen stores and increased oxygen consumption. Moreover, the rate of difficult airway management may be higher in the intensive care unit (ICU) and in the Emergency Department (ED), prolonging the apnea time and the risk of desaturation. Finally, operator’s skills, procedures, devices and drugs, among others, may influence airway management success and patient’s outcome. Despite the high risk of the procedure, different interventions lack high-quality evidence and we hypothesize that a heterogeneous practice among different centres and geographical areas may be found . This project aims to prospectively collect data on the current impact of ETI-related adverse events and current airway management practice in critically ill patients. This is an observational multi-centre international cohort study from different centres (at least 180 centres) all over the world. Each centre has to collect data of 20 endotracheal intubations over a maximum period of 8 weeks.

**Objectives of the study**

a) The primary aim of this study is to evaluate the incidence of intubation-related adverse events in critically ill patients.

b) Secondary aim is to evaluate current clinical practices on airway management in the in-hospital critical care setting.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-02
• Last Update Posted: 2019-01-22

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 3600

Inclusion Criteria

• 1. We will include all adult (equal or more than 18 years old) critically ill patients undergoing intubation during the period of observation.
• 2. We will consider all in-hospital intubations.

Exclusion Criteria

1. Intubation performed in the out-of-hospital setting 2) Intubation during cardiac arrest 3) Intubation performed for anaesthesia (during either diagnostic/endoscopic or surgical procedures).

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the incidence of intubation related adverse	3 different time points
events in critically ill patients	3 different time points

Secondary Outcome Measures

Name	Time	Method
To evaluate current clinical practices on airway management in the in-hospital critical care setting	3 different time points

Trial Locations

Locations (1)

National Institute of Mental Health and Neurosciences; 🇮🇳 Bangalore, KARNATAKA, India

National Institute of Mental Health and Neurosciences

🇮🇳Bangalore, KARNATAKA, India

Gopalakrishna K N

Principal investigator

9916469626

gops868@gmail.com