Role of Milrinone in the Prevention of Septic Myocardial Dysfunction in Pediatric Severe Sepsis and Septic Shock

Not Applicable

• Conditions: Paediatrics; Cardiology

• Registration Number: PACTR202302881132303
• Lead Sponsor: Pediatric Department Alexandria University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-02-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Children with severe sepsis/septic shock after resuscitation according to pediatric 2020 surviving sepsis campaign international guidelines( SSC)
- Children with a cardiac index of more than 2.2 l/min/m2.

Exclusion Criteria

- Patients with primary myocardial diseases or congenital heart or chronic heart disease.
- Patients with significant left ventricular outflow tract obstruction or the need for extracorporeal membrane oxygenation.
- Patients receiving chemotherapeutic agents.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Development of low cardiac output syndrome <br>;Death

Secondary Outcome Measures

Name	Time	Method
Duration of Pediatric Intensive Care Unit stay<br>;Duration of mechanical ventilation