Milrinone for the treatment of raised pressure in the lung vessels in neonates
Phase 3
- Conditions
- Health Condition 1: P293- Persistent fetal circulation
- Registration Number
- CTRI/2019/11/021896
- Lead Sponsor
- JIPMER Puducherry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Infants of all gender with Gestational age >34 weeks and birth weight >=1800g
2. <14 days of age
3.Echocardiographic diagnosis of PPHN
4.Requirement for mechanical ventilation
Exclusion Criteria
1.Major congenital anomalies or syndromes including congenital diaphragmatic hernia
2.Any congenital heart disease
3.Clinically evident bleeding diathesis or platelet count <50,000/cmm
4.Hypotension refractory to usual medical treatment (>=20 mL/kg fluid bolus and >=2 inotropes)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of mechanical ventilationTimepoint: at discharge
- Secondary Outcome Measures
Name Time Method eonatal mortality <br/ ><br>Duration of oxygen therapy <br/ ><br>Duration of hospital stay <br/ ><br>Timepoint: 28 days <br/ ><br>at discharge <br/ ><br>at discharge