Predictors of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis
- Conditions
- Pulmonary HypertensionHypersensitivity Pneumonitis
- Interventions
- Procedure: Right heart catheter
- Registration Number
- NCT05458635
- Lead Sponsor
- Cairo University
- Brief Summary
Hypersensitivity pneumonitis (HP) is a complex immune mediated disorders caused by repeated inhalation of and sensitization to wide range of antigens including organic particles and chemical compounds, leading to exaggerated immuneresponse. Hypersenstivity pneumonitis is a common form of diffuse parenchymal lung diseases in Egypt .Pulmonary hypertension has been found as a complication of a number of diseases affecting the lung interstitium, including hypersensitivity pneumonitis, with subsequent affection of the life expectancy Rationale of the study: to find predictors for the development of pulmonary hypertension in patients with hypersensitivity pneumonitis
- Detailed Description
Cross sectional study included 60 patients with established diagnosis of HP , work up includes history of exposure, clinical examination, HRCT chest, ABGs,6MWD, desaturation degree , spirometry, echocardiography and right heart catheter in patients with high echo probability of PH.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- All patients with confirmed diagnosis of Hypersensitivity pneumonitis
- Other interstitial lung diseases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description HP with Pulmonary hypertion Right heart catheter HRCT chest , pulmonary functions ,echocardiography and RT heart catheter in high echocardiographic probability of PH
- Primary Outcome Measures
Name Time Method Percentage of pulmonary hypertension in patients with HP 6 months primary oucome
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kasr alainy school of medicine
🇪🇬Cairo, Egypt