The Identification and Characterization of Autonomic Dysfunction in Migraineurs With and Without Auras

Completed

• Conditions: Migraine

• Registration Number: NCT01080287
• Lead Sponsor: The Cleveland Clinic

Brief Summary

This is a study to compare subject response and symptoms resulting from administration of three clinical assessments.

\* The 3 assessments are

1. passive upright tilt table testing,

2. quantitative sudomotor axon reflex testing (QSART)and

3. punch biopsy.

The comparison of results will be from two subject groups:

* Group A, the migraine suffering patient with or without aura

* Group B, the migraine suffering patient with or without aura who has diagnosed orthostatic intolerance (i.e.,feeling dizzy or faint when making a body position change).

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2010-03-02
• Study First Submitted QC: 2010-03-03
• Study First Posted: 2010-03-04
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2012-02
• Last Update Submitted: 2012-02-20
• Last Update Posted: 2012-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• age 18 to 65
• male or female
• migraine diagnosis
• may or may not have orthostatic intolerance
• able to demonstrate study understanding and complete informed consent process

Exclusion Criteria

• subjects who do not meet inclusion criteria
• subjects unable to complete informed consent process

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Cleveland Clinic NI, Center for Headache and Pain, Desk T-33, 9500 Euclid Avenue; 🇺🇸 Cleveland, Ohio, United States