“COMPARISON OF PROPOFOL AND ETOMIDATE -TWO INTRAVENOUS ANAESTHETIC AGENTS TO ASSESS STRESS RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATIONâ€

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/09/045366
• Lead Sponsor: CIVIL HOSPITALGOVERNMENT OF GUJARAT

Brief Summary

DESPITE ADEQUATE ANAESTHETIC DEPTH, DIRECT LARYNGOSCOPY AND INTUBATION ELICIT A SIGNIFICANT ADRENO-SYMPATHETIC RESPONSE. THE RESPONSE, AS MANIFESTED BY CHANGE IN BLOOD PRESSURE(BP), HEART RATE(HR), ARRYTHMIAS, etc. THE PRESENT STUDY WAS UNDERTAKEN TO COMPARE PROPOFOL AND ETOMIDATE AS AN INDUCTION AGENT TO EVALUATE HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-03-09
• Study Start: 2022-09-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ASA 1,2,3 PATIENTS POSTED FOR GENERAL SURGERY FOR SURGERY UNDER GENERAL ANESTHESIA REQUIRING ENDOTRACHEAL INTUBATION.

Exclusion Criteria

• Refusal to give consent Age<12yrs ASA grade IV.
• V Known allergies to anaesthetic drugs Patients hemodynamically or neurologically unstable Patient having neurological or psychiatric disorder.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EVALUATION OF PROPOFOL VS ETOMIDATE AS AN INDUCTION AGENT TO HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION.	FROM THE TIME OF INDUCTION TO 30 MIN POST ENDOTRACHEAL INTUBATION

Secondary Outcome Measures

Name	Time	Method
CHANGES IN INTRA-OPERATIVE HEMODYNAMIC CHANGES	ANY COMPLICATIONS LIKE APNEA, MYOCLONUS

Trial Locations

Locations (1)

GENERAL SURGERY OPERATION THEATERS; 🇮🇳 Ahmadabad, GUJARAT, India

GENERAL SURGERY OPERATION THEATERS

🇮🇳Ahmadabad, GUJARAT, India

YOGESH PALIWAL

Principal investigator

8814071212

dr.yogeshpaliwal12@gmail.com