Effect of Modified Atkins diet when compared to Low Glycemic Index diet in controlling seizures in children with epilepsy who do not respond to conventional anti epileptic drugs
Not Applicable
- Conditions
- Health Condition 1: null- Drug resistant epilepsy
- Registration Number
- CTRI/2017/12/010898
- Lead Sponsor
- Jaya Shankar Kaushik
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children aged 6 months to 5 years with drug resistant epilepsy (failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom)
Exclusion Criteria
(i) Children with known or suspected inborn error of metabolism.
(ii) Children with renal, pulmonary, cardiac or hepatic dysfunction.
(iii) Severe malnutrition (weight for length and height for age less than 3 SD for mean as per WHO growth charts),
(iv) Children from families who lack motivation will also be excluded as it might affect the compliance
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of children who achieved seizure freedom as per parental reports at 4 weeks and 12 weeks in both the groupsTimepoint: 4 weeks <br/ ><br>12 weeks
- Secondary Outcome Measures
Name Time Method Description and proportion of adverse effect of diet as reported by parentsTimepoint: four and twelve weeks;proportion of children who achieved more than fifty percent reduction in seizure as per parental reportTimepoint: four and twelve weeks;Proportion of children who achieved more than ninty percent reduction in seizure as per parental reportTimepoint: four and twelve weeks