Evaluation of Bacterial and Fungal Contamination During Propofol Continuous Infusion in Patients Undergoing General Anesthesia
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- University of Sao Paulo
- Enrollment
- 652
- Locations
- 1
- Primary Endpoint
- Existence of bacterial and/or fungal contamination during different technics of propofol continuous infusion
Study Overview
Brief Summary
The purpose of this study is to verify the existence of bacterial and/or fungal contamination during different technics of propofol with or without EDTA continuous infusion in patients undergoing general anesthesia.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Single Group
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age eighteen years old or more
- •ASA Physiological Status P1 ou P2
- •Patients undergoing clean procedure under general anesthesia.
Exclusion Criteria
- •Patients under eighteen years old
- •ASA Physiological Status P3, P4 or P5
- •Current infectious process
Arms & Interventions
1
TCI with EDTA
Intervention: EDTA without re-filling (Drug)
2
Re-filling of propofol syringe (Diprivan®-Astra Zeneca) with propofol containing EDTA
Intervention: Propofol syringe re-filling with propofol containing EDTA (Other)
3
Re-filling of propofol syringe (Diprivan®-Astra Zeneca) with propofol without EDTA
Intervention: Re-filling of syringe with propofol without EDTA (Other)
4
Target controlled infusion of propofol without EDTA
Intervention: Target controlled infusion of propofol without EDTA (Other)
Outcomes
Primary Outcomes
Existence of bacterial and/or fungal contamination during different technics of propofol continuous infusion
Time Frame: 6 months
Secondary Outcomes
No secondary outcomes reported