The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis

• Conditions: Dacryocystitis; Bacteriology

• Registration Number: NCT03216642
• Lead Sponsor: Sun Yat-sen University

Brief Summary

An observational study was designed to research the bacteriology and pathogen drug sensitivity of chronic dacryocystitis in China and optimize antibiotic therapy.

Detailed Description

For patients diagnosed with chronic dacryocystitis，we will collect the secretions after lacrimal passage irrigation, note the characters of the secretions and send the secretions for bacteria culture, analysis and pathogen drug sensitivity.

Study Timeline

• Status Verified: 2017-07
• Study First Submitted: 2017-07-07
• Study First Submitted QC: 2017-07-12
• Study First Posted: 2017-07-13
• Study Start: 2017-07-17
• Last Update Submitted: 2017-07-26
• Last Update Posted: 2017-07-27
• Primary Completion: 2018-04-17
• Study Completion: 2018-04-17

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Diagnosed with chronic dacryocystitis
2. No involvement in other drug experiment in the past 1 week

Exclusion Criteria

1. Can not cooperate the specimen collection
2. With any other eye disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bacterial agents	2 weeks	Specimens will be collected after irrigation of the lacrimal passage and be sent for bacterial culture and bacterial analysis.

Secondary Outcome Measures

Name	Time	Method
Sensitivity test	2 weeks	The drugs tested include Penicilin, Amikacin, Azithromycin, Cefoxitin, Levofloxacin，Ofloxacin, Cefuroxime and Tobramycin.
The colour of lacrimal sac secretion	2 weeks	The colour of lacrimal sac secretion will be identified by the doctor during the irrigation of the lacrimal passage.
The character of lacrimal sac secretion	2 weeks	The lacrimal sac secretion will be classified as mucus or pus.

Trial Locations

Locations (1)

Clinical Research Center; 🇨🇳 Guangzhou, Guangdong, China