MedPath

Oat Phenolics Bioavailability

Not Applicable
Completed
Conditions
Healthy
Registration Number
NCT02574039
Lead Sponsor
University of Reading
Brief Summary

A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
7
Inclusion Criteria
  • Males
  • 25 to 65 years old
Exclusion Criteria
  • Allergies to oats
  • Parallel participation in another research project
  • Having flu vaccination or antibiotics within 3 months of trial start
  • Taking food supplements within 3 months of trial start
  • Past or existing medical history of vascular disease, diabetes, hepatic, renal, gastrointestinal, haematological, neurological, thyroidal disease or cancer

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Change from baseline in phenolic acid metabolite excretionBaseline and 48 hours
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Food and Nutritional Sciences

🇬🇧

Reading, Berkshire, United Kingdom

Department of Food and Nutritional Sciences
🇬🇧Reading, Berkshire, United Kingdom

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