Oat Phenolics Bioavailability

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT02574039
• Lead Sponsor: University of Reading

Brief Summary

A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-06-26
• Study Start: 2015-07
• Status Verified: 2015-10
• Primary Completion: 2015-10
• Study Completion: 2015-10
• Study First Submitted QC: 2015-10-09
• Last Update Submitted: 2015-10-09
• Study First Posted: 2015-10-12
• Last Update Posted: 2015-10-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 7

Inclusion Criteria

• Males
• 25 to 65 years old

Exclusion Criteria

• Allergies to oats
• Parallel participation in another research project
• Having flu vaccination or antibiotics within 3 months of trial start
• Taking food supplements within 3 months of trial start
• Past or existing medical history of vascular disease, diabetes, hepatic, renal, gastrointestinal, haematological, neurological, thyroidal disease or cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Change from baseline in phenolic acid metabolite excretion	Baseline and 48 hours

Trial Locations

Locations (1)

Department of Food and Nutritional Sciences; 🇬🇧 Reading, Berkshire, United Kingdom