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临床试验/NCT02574039
NCT02574039已完成不适用

Absorption, Metabolism and Excretion of Oat Phenolic Acids in Healthy Men.

University of Reading2 个研究点 分布在 1 个国家目标入组 7 人开始时间: 2015年7月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
7
试验地点
2
主要终点
Change from baseline in phenolic acid metabolite excretion

研究概览

简要总结

A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
25 Years 至 65 Years(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • 25 to 65 years old

排除标准

  • Allergies to oats
  • Parallel participation in another research project
  • Having flu vaccination or antibiotics within 3 months of trial start
  • Taking food supplements within 3 months of trial start
  • Past or existing medical history of vascular disease, diabetes, hepatic, renal, gastrointestinal, haematological, neurological, thyroidal disease or cancer

结局指标

主要结局

Change from baseline in phenolic acid metabolite excretion

时间窗: Baseline and 48 hours

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jeremy Paul Edward Spencer

Professor

University of Reading

研究点 (2)

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