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Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements in Blood Glucose

Not Applicable
Active, not recruiting
Conditions
PreDiabetes
Type 2 Diabetes Mellitus
Interventions
Behavioral: High-effort session
Behavioral: Low-effort session
Behavioral: Control
Registration Number
NCT06208189
Lead Sponsor
University of New Mexico
Brief Summary

The goal of this clinical trial is to compare the degree of effort during a resistance exercise session on blood glucose levels in individuals with prediabetes or type 2 diabetes mellitus. The main questions it aims to answer are:

* Do individuals with prediabetes or type 2 diabetes mellitus need to perform resistance exercise with a high degree of effort for their blood glucose to improve?

* How do they feel (their enjoyment, discomfort) after the sessions with different degrees of effort?

Participants will perform 3 situations separated by at least 4 days, after being familiarized with all exercises and procedures:

* One control day, when they will not exercise;

* A high-effort resistance exercise session;

* A low-effort resistance exercise session Researchers will measure blood glucose levels and psychological responses after these situations to see if the effort was important for the improvement of their blood glucose and how effort affected the way they felt after each situation.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
15
Inclusion Criteria
  • age between 18 and 75 years;
  • presence of prediabetes (fasting glycemia between 100 and 125 mg/dL or glycated hemoglobin [A1c] between 5.7 and 6.4%) or T2DM (fasting glycemia 126 mg/dL or above or A1c 6.5% or above).
Exclusion Criteria
  • renal failure,
  • liver disease,
  • uncontrolled hypertension (equal or greater than 160 mmHg systolic and/or equal or greater than 100 mmHg diastolic),
  • history of severe cardiovascular problems,
  • in case of oral hypoglycemic drugs usage, being on them for less than 6 months,
  • inability to perform resistance exercise,
  • being pregnant or trying to become pregnant during the course of the study,
  • use of oral contraceptives,
  • prisoners,
  • persons requiring a legally authorized representative,
  • non-English speakers.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
high-effort sessionHigh-effort sessionParticipants will perform sets with as many repetitions they can each set.
low-effort sessionLow-effort sessionParticipants will perform sets with half of the anticipated number of repetitions of the high-effort session.
Control sessionControlThe control session all procedures will be identical to the high-effort session.
Primary Outcome Measures
NameTimeMethod
Prevalence of hypoglycemiaFor 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study

Time of glucose concentrations \<70 mg/dL (measured in minutes)

Time in rangeFor 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study

Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)

Glucose concentrationFor 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study

Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)

Prevalence of hyperglycemiaFor 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study

Time of glucose concentrations \>180 mg/dL (measured in minutes)

Secondary Outcome Measures
NameTimeMethod
Rating of Discomfort scaleBefore and 5 minutes after the resistance exercise sessions.

Discrete scale from 0 to 100, where higher scores mean more discomfort.

Resistance Training Intensity by the Omni Perceived Exertion ScaleAfter each set of each exercise performed.

Discrete scale from 0 to 10, where higher values mean more perceived exertion.

Feeling scaleBefore and immediately after the resistance exercise sessions.

Discrete scale from -5 to +5, where higher values mean more positive feelings.

Physical Activity Enjoyment ScaleImmediately after the resistance exercise sessions.

Scale composed of 18 items, with scores from 1 to 7 each (total score from 18 to 126). After analysis, higher scores mean higher enjoyment.

Self-efficacy scaleImmediately after the resistance exercise sessions.

Scale composed of 8 questions, with discrete options from 0 to 100%. Higher scores mean higher self-efficacy.

Session rating of perceived exertion5 minutes after the resistance exercise sessions.

Discrete scale from 0 to 10, where higher values mean more perceived exertion.

Trial Locations

Locations (1)

UNM Exercise Physiology Lab

🇺🇸

Albuquerque, New Mexico, United States

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