The impact of treating rheumatoid arthritis on sleep
Not Applicable
- Conditions
- Rheumatoid arthritis (RA), Obstructive sleep apnea (OSA)
- Registration Number
- JPRN-UMIN000024595
- Lead Sponsor
- Graduate School of Medicine, Kyoto University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
# Patients who have difficulty with wearing measuring equipment due to dementia, physically handicapped, and so on # Patients who have had treatment with methotrexate in the past and the present treatment will be re-admininstration of methotraxate # Patients who is considered as inappropriate by a main researcher
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The score of Pittsburgh Sleep Quality Index (PSQI) of before and after treatment in patients with RA
- Secondary Outcome Measures
Name Time Method 1. Sleep duration 2. The index of sleep disturbance (wake after sleep onset, sleep efficiency, sleep fragmentation, sleep latency, peripheral artery tonometry apnea hypopnea index, 3 and 4% oxygen desaturation index, time spent with SpO2 below 90%, the lowest SpO2, sleep stage) 3. Questionnaires including quality of life (Japan-Epworth Sleepiness Scale, Medical Outcomes Study 36-Item Short Form Health Survey, Hospital Anxiety and Depression Scale, Physical Activity, The Berline Questionnaire) 4. The prevalence of OSA 5. The prevalence of restless leg syndrome 6. The disease activity of RA 7. Psychomotor vigilance task 8. Physical activity measured by life coda and actiwatch 9. Blood sample including inflammatory cytokines and matrix metalloproteinase, urinalysis 10. Pulmonary function test 11. X ray, chest CT 12. Vascular endothelial function