PAS for Lower Extremity Rehabilitation in Tetraplegic Patients
Not Applicable
Completed
- Conditions
- Spinal Cord DiseasesSpinal Cord Injuries
- Interventions
- Device: Paired associative stimulation (with eXimia magnetic stimulator and Dantec Keypoint® electroneuromyography device)
- Registration Number
- NCT03459885
- Lead Sponsor
- Helsinki University Central Hospital
- Brief Summary
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles (1,2). In this study, the investigators will administer long-term paired associative stimulation to patients with incomplete cervical level SCI and investigate its effectiveness for lower extremity rehabilitation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
- cervical incomplete SCI
Exclusion Criteria
- epilepsy
- metal inclusion in the head area
- pacemaker
- hearing device
- high intracranial pressure
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description PAS Paired associative stimulation (with eXimia magnetic stimulator and Dantec Keypoint® electroneuromyography device) The intervention is given to peripheral nerve - motor cortex pairs selected by the investigator.
- Primary Outcome Measures
Name Time Method Daniels and Worthingham's Muscle Testing 1 month after the last stimulation session leg muscles are evaluated on 0-5 scale
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
BioMag laboratory, Helsinki University Central Hospital
🇫🇮Helsinki, Uusimaa, Finland