Long-term PAS in Rehabilitation After SCI

Not Applicable

Completed

• Conditions: Spinal Cord Injuries
• Interventions: Device: long-term paired associative stimulation

• Registration Number: NCT03045744
• Lead Sponsor: Helsinki University Central Hospital

Brief Summary

The investigators have recently shown in two pilot incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles (1). In this study, the investigators will administer long-term paired associative stimulation to incomplete SCI patients in a long-term manner, keeping each patient in the study for as long as continuous improvement is observed.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-02-02
• Study First Submitted QC: 2017-02-03
• Study First Posted: 2017-02-07
• Study Start: 2017-02-10
• Primary Completion: 2023-06-01
• Study Completion: 2023-12-01
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-12
• Last Update Posted: 2025-05-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

• incomplete SCI

Exclusion Criteria

• epilepsy
• metal inclusion in the head area
• pacemaker
• hearing device
• high intracranial pressure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
incomplete SCI patients	long-term paired associative stimulation	-

Primary Outcome Measures

Name	Time	Method
Daniels and Worthingham's Muscle Testing	1 month after the last stimulation session

Trial Locations

Locations (1)

BioMag laboratory, Helsinki University Central Hospital; 🇫🇮 Helsinki, Uusimaa, Finland