Haemodynamic Effects Of Intravenous Paracetamol In Healthy Volunteers
Phase 4
Completed
- Conditions
- Blood pressure in Healthy VolunteersCardiac output in Health VolunteersSystemic vascular resistance in Healthy volunteersCardiovascular - Normal development and function of the cardiovascular system
- Registration Number
- ACTRN12615000533594
- Lead Sponsor
- Austin Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
1. Adults (age >18 years but less than 60 years)
2. Healthy Volunteers
3. No regular medications
Exclusion Criteria
Paracetamol use 24 hours prior to trial (in paracetamol only or in combination therapy)
Pregnancy
Chronic renal impairment (Creatinine >120 umol/L)
Chronic liver disease (ALT >100IU/L)
Morbid obesity (BMI >35kg/m2)
Known allergic reaction to IV paracetamol, mannitol or normal saline
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method