Gut Permeability and Stress

Completed

• Conditions: Stress
• Interventions: Other: Trier social stress test

• Registration Number: NCT02485405
• Lead Sponsor: Lund University

Brief Summary

The purpose of this study is to analyse gut permeability and stress.

Detailed Description

Healthy male volunteers (aged 19-35 years) participate in Trier social stress test while saliva and blood samples are withdrawn.

Saliva will be used for analysis of cortisol and blood will be used for analysis of various biomarkers.

Study Timeline

• Study Start: 2015-06
• Study First Submitted: 2015-06-23
• Study First Submitted QC: 2015-06-25
• Study First Posted: 2015-06-30
• Status Verified: 2017-09
• Primary Completion: 2017-09
• Study Completion: 2017-09
• Last Update Submitted: 2017-09-06
• Last Update Posted: 2017-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 45

Inclusion Criteria

• Man, 19-35 years old
• Healthy

Exclusion Criteria

• Psychological disorders
• Use of antibiotics or other drugs

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
stressed	Trier social stress test	stressed volunteers perform Trier social stress test
non-stressed	Trier social stress test	non-stressed volunteers perform Trier social stress test

Primary Outcome Measures

Name	Time	Method
gut permeability (marker measured in plasma/serum) in healthy young men participating in Trier social stress test	Volunteers will be followed by one hour after Trier social stress test

Trial Locations

Locations (1)

Lund University; 🇸🇪 Lund, Sweden