A research study to reduce the death rate of Russels viper snake bite patients by using Antisnake venom.
Phase 3
- Conditions
- Health Condition 1: T630- Toxic effect of snake venom
- Registration Number
- CTRI/2022/12/048418
- Lead Sponsor
- GOVERNMENT VILLUPURAM MEDICAL COLLEGE AND HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
(a)Patients aged >18 years with H/o bite by Russelâ??s viper [visually identified]
(b)Presenting within 6 hours to our institute.
(c)Clinical signs of systemic envenomation warranting ASV, and/or
(d)Abnormal WBCT [ >20 minutes, incoagulable].
Exclusion Criteria
(a)Patients with CKD
(b)Heart failure
(c)Pregnancy
(d)Age >65 years.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MORTALITYTimepoint: 28 DAY
- Secondary Outcome Measures
Name Time Method 1. Dosage of ASV needed <br/ ><br>2. Time to normalization of WBCT <br/ ><br>3. Time to normalization of PT/INR/APTT. <br/ ><br>4. Time to clinical recovery <br/ ><br>5. Time to hemodynamic stabilization <br/ ><br>6. Need for FFP <br/ ><br>7. Dosage of FFP needed <br/ ><br>8. Duration of ICU stay. <br/ ><br>9. Need for RENAL REPLACEMENT THERAPY <br/ ><br>10. Need for Mechanical Vent Support [MVS] <br/ ><br>11. Duration of MVS <br/ ><br>12. Need for fasciotomy/ amputation. <br/ ><br>Timepoint: 28 DAY