Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery

Not Applicable

• Conditions: Hypoparathyroidism; Marker; Structural; Complication of Surgical Procedure; Thyroid Cancer; Parathyroid Function Low Adverse Event
• Interventions: Procedure: The suture marks the location of the parathyroid gland

• Registration Number: NCT03514251
• Lead Sponsor: Bo Wang,MD

Brief Summary

To study the protective effect of suture parathyroid marker method on the function of parathyroid gland in thyroid cancer surgery

Detailed Description

This is a prospective randomized controlled study.In the experimental group, the suture parathyroid marker method was used to mark the parathyroid gland at the first time when it shows, and this marker was further used to identify and locating the inferior parathyroid marker in subsequent central region dissection. In the control group, the central area was routinely cleaned without suture parathyroid marker .

Study Timeline

• Status Verified: 2018-04
• Study Start: 2018-04-01
• Study First Submitted: 2018-04-20
• Study First Submitted QC: 2018-04-20
• Last Update Submitted: 2018-04-20
• Study First Posted: 2018-05-02
• Last Update Posted: 2018-05-02
• Primary Completion: 2018-09-30
• Study Completion: 2018-09-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Patients with thyroid cancer who need central compartment dissection
• Routine neck incision surgery
• Patients undergoing primary neck surgery

Exclusion Criteria

• Benign thyroid tumor patients
• Selecting patients with endoscopes, small incisions, or robotic surgery
• Patients with hyperparathyroidism

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Parathyroid marker group	The suture marks the location of the parathyroid gland	When the lower parathyroid gland is first seen, the parathyroid gland is sutured with a suture during the operation, and then during this subsequent cleaning, rapid parathyroid localization and parathyroid glands are performed through this marker.

Primary Outcome Measures

Name	Time	Method
The stitch marking operation time	During surgery	The time required for making a parathyroid marker by a suture method
Specimen inspection time	During surgery	The time required for finding parathyroid glands in surgical specimens
The number of transplanted parathyroid glands	When the surgery is completed	The number of parathyroid glands required for autotransplantation of parathyroid glands
Parathyroid hormone level testing	0 days, 1 day, 2 weeks after surgery	Parathyroid hormone levels before and after surgery
Calcium levels	0 days, 1 day, 2 weeks after surgery	Calcium level before and after surgery to detect

Trial Locations

Locations (1)

Fujian Medical University Union Hospital; 🇨🇳 FuZhou, Fujian, China