Disease manifestation and disease management in chronic heart failure

Not Applicable

Completed

• Conditions: Chronic heart failure; Circulatory System; Heart failure

• Registration Number: ISRCTN23325295
• Lead Sponsor: niversity of Würzburg

Brief Summary

2009 publication (in German) on the interventions used in this study in https://www.ncbi.nlm.nih.gov/pubmed/19340758 2011 secondary analysis of prevalence of major and minor depression in https://pubmed.ncbi.nlm.nih.gov/19716613/ (added 25/01/2021) 2012 INH results in https://www.ncbi.nlm.nih.gov/pubmed/21956192 2012 secondary analysis on dysnatraemia in https://pubmed.ncbi.nlm.nih.gov/22820314/ (added 21/12/2020) 2013 secondary analysis of participants with subclinical thyroid dysfunction in https://pubmed.ncbi.nlm.nih.gov/23041000/ 2014 secondary analysis of mortality reduction in depressed and non-depressed participants in https://pubmed.ncbi.nlm.nih.gov/25142121/ (added 21/12/2020) 2015 secondary analysis of prognostic value of depressive symptoms in https://pubmed.ncbi.nlm.nih.gov/25770643/ (added 21/12/2020) 2015 secondary analysis of PHQ-2 and PHQ-9 and correlation with death or rehospitalisation in https://pubmed.ncbi.nlm.nih.gov/25878325/ 2015 secondary analysis of prescribing in https://pubmed.ncbi.nlm.nih.gov/25727879/ (added 21/12/2020) 2016 secondary analysis of salivary cortisol levels in https://pubmed.ncbi.nlm.nih.gov/26492313/ (added 15/01/2021) 2017 secondary analysis of prognostic potential of midregional pro-adrenomedullin (MR-proADM) in https://pubmed.ncbi.nlm.nih.gov/28516504/ (added 15/01/2021) 2017 secondary analysis of association of NPSR1 gene variants with death, rehospitalisation and healthcare utilisation in https://pubmed.ncbi.nlm.nih.gov/27990720/ (added 15/01/2021) 2018 secondary analysis of associations between CRP genetic variants, mortality and depression in https://pubmed.ncbi.nlm.nih.gov/29627531/ (added 15/01/2021) 2019 secondary analysis of participants hospitalised for systolic heart failure in https://www.ncbi.nlm.nih.gov/pubmed/30553401 (added 27/02/2020) 2019 secondary analysis of sex and gender differences in PHQ-9 and HRQOL responses in https://pubmed.ncbi.nlm.nih.gov/30097684/ (added 15/01/2021) 2021 secondary analysis of LVEF trajectories after acute cardiac decompensation of heart failure in https://pubmed.ncbi.nlm.nih.gov/33496189/ (added 27/01/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-11-30
• Study Completion: 2018-10-10
• Last Update Posted: 8 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1032

Inclusion Criteria

1. Age >18 years
2. Written informed consent
3. Heart failure documented by reduced left ventricular ejection fraction (<=40%) during hospitalisation and clinical signs/symptoms of heart failure (peripheral edema, pulmonary edema, rales, pulmonary congestion confirmed by X-ray, elevated jugular venous pressure, exertional dyspnea)

Exclusion Criteria

1. Insufficient mental or verbal or physical ability to participate in a telephone assisted monitoring and education program
2. No telephone line installed

Study & Design

• Study Type: Interventional
• Study Design: Not specified