NL-OMON50610
Withdrawn
Not Applicable
Immunological and Genetic Risk factors for Cardiac Serious Adverse Events following Controlled Human Malaria Infections: a Case-Control study - Risk factors for cardiac SAEs following CHMI
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Myocarditis (inflammation of the heart muscle) and acute coronary syndrome (range of conditions associated with sudden
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 25
- Status
- Withdrawn
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •In order to be eligible to participate in this study as a case, a subject must
- •meet all of the following criteria:
- •1\. Subject must sign written informed consent to participate in the trial.
- •2\. By judgement of the clinical investigator, the subject is able to understand
- •the planned study procedures and (limited) risks associated with the study,
- •inc. the risk of incidental findings in genetic analysis.
- •3\. The subject was enrolled in a CHMI study performed by the Radboudumc between
- •January 1998 and December 2021 and was subjected to a Controlled Human Malaria
- •Infection. Subject developed a cardiac serious adverse event in the period of
- •20 days following CHMI. A cardiac SAE is defined as either clinically
Exclusion Criteria
- •A potential case or control subject who meets any of the following criteria
- •will be excluded from participation in immunological screening:
- •1\. Subject is HIV\-positive or suffers from any other (acute or chronic) disease
- •as determined by medical history, physical examination or laboratory screening
- •tests which according to the clinical judgment of the investigator leads to
- •undesirable interference with the results of the immunological tests. The
- •clinical investigator will consider whether blood samples without such
- •interference can be obtained later in the study period (e.g. in case of acute
- •infectious disease).
- •2\. Use or receipt of
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Not Applicable
Genetic Study in patients with high risk for cardiovascular eventsAtherosclerosis patients or having at least 3 risks factor of atherosclerosis such as DM,HTgenotype, genetic marker, cardiovascular disease, diabetes, hypertension, obesityTCTR20210824008Health Systems Research Institute3,000
Active, not recruiting
Not Applicable
Exercise, chronic fatigue syndrome and multiple sclerosisMultiple Sclerosis (MS)Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS)Neurological - Multiple sclerosisPhysical Medicine / Rehabilitation - Other physical medicine / rehabilitationOther - Conditions of unknown or disputed aetiology (such as chronic fatigue syndrome/myalgic encephalomyelitis)ACTRN12614001309673Massey University21
Recruiting
Not Applicable
Genetic Risk factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID condition (GRIP)NL-OMON53446eids Universitair Medisch Centrum400
Recruiting
Not Applicable
Heart muscle disorderHealth Condition 1: null- CardiomyopathyCTRI/2017/11/010532ICMR
Not yet recruiting
Not Applicable
Identification of Genetic and Hereditary factors affecting young adults with cardiac diseases.CTRI/2015/12/006467Medanta The Medicity1,000