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Registry of Food Allergy Oral Immunotherapy Treatment

Completed
Conditions
Food Allergy
Registration Number
NCT03059589
Lead Sponsor
Food Allergy Support Team
Brief Summary

The purpose of this patient registry is to demonstrate safety and efficacy of food oral immunotherapy in food allergic patients. Factors that lead to adverse reactions will be identified. The frequency of rescue epinephrine use will be recorded.

Detailed Description

Each participating US clinic is assigned a site number and patients starting food oral immunotherapy will be given a four digit number starting at 0001 within each site. All data will be collected and reported electronically at each clinical site.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2000
Inclusion Criteria
  • a history of an allergic reaction following exposure to the food and positive in-vivo or in-vitro sensitivity testing to the food,
  • no prior exposure to the food, but markedly high in-vitro specific immunoglobulin E (IgE) to the food
Exclusion Criteria
  • pregnancy
  • severe asthma
  • poorly controlled atopic dermatitis
  • eosinophilic esophagitis

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
efficacy of food allergy treatment3 years

the percentage of patients who successfully reach the maintenance dose of food

Secondary Outcome Measures
NameTimeMethod
epinephrine use3 years

The frequency of epinephrine use during the course of oral immunotherapy as reported in the prospective database. Also, identify factors that are associated with the need for epinephrine.

factors associated with the failure to reach the target dose of food ingestion3 years

Identify factors that are associated with treatment failures through analysis of patient demographics, baseline laboratory test results, and concomitant atopic conditions.

Trial Locations

Locations (1)

Food Allergy Center of FL

🇺🇸

Sarasota, Florida, United States

Food Allergy Center of FL
🇺🇸Sarasota, Florida, United States

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