Effect of different perioperative prophylaxis with antibiotics in pediatric cardiac surgery on the incidence of infectious complications
Not Applicable
Recruiting
- Conditions
- Pediatric patients with congenital heart desease (CHD) and the need for surgical correction, e. g. atrial septal defect (Q 21.1) but also every other CHD.Q21.1Atrial septal defect
- Registration Number
- DRKS00004445
- Lead Sponsor
- niversitätsklinikum des Saarlandes
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Pediatric patients up to the age of 18 years with congenital heart disease and with the need of surgical intervention
- Written consent of the parents/persons who have the care and custody of the children and, depending on the age, of the patients capable of insight, all children and adolescents aged 0 to 18 years
Exclusion Criteria
- Absent of written consent
- Known allergic reactions or incompatibility of the planned antibiotics
- Indication for delayed sternal closure
- Known colonisation with multi-drug resistant bacteria
- Antibiotic treatment within the last 7 days preoperatively
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Appearance of wound infections and other infections:<br>- clinical assessment preoperatively, on admission to ICU and in the course of time in hospital<br>- blood work preoperatively, on admission to ICU and day one and three postoperatively (e. g. CrP, Procalitonin, WBC)
- Secondary Outcome Measures
Name Time Method - Positive culture from foreign bodies, i. e. CVL, thoracic drainage, tube, pacing wires<br>- Duration of ventilation<br>- Stay in ICU<br>- Stay in hospital<br>- CrP and Procalzitonin<br>- Endocarditis up to 6 months postoperatively