The inhibitory effect of metformin on gluconeogenesis in relation to polymorphisms in Organic Cation Transporter 1 (OCT1) in healthy volunteers
Phase 1
- Conditions
- Healthy volunteers (diabetes mellitus 2)MedDRA version: 14.1Level: LLTClassification code 10045242Term: Type II diabetes mellitusSystem Organ Class: 10027433 - Metabolism and nutrition disordersTherapeutic area: Body processes [G] - Metabolic Phenomena [G03]
- Registration Number
- EUCTR2011-001696-39-DK
- Lead Sponsor
- niversity of Southern Denmark, Clinical Pharmacology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
inclusion criteria:
Health
Age 18-65 years
Caucasian
Included in The Pharmacogenomics Biobank of the University of Southern Denmark
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 36
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range 0
Exclusion Criteria
Daily medication
Alcohol abuse
Pregnancy
Breastfeeding
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method