Angiogenesis in Early Breast Cancer for Prognosis Prediction
Not Applicable
Completed
- Conditions
- Breast Lesions
- Registration Number
- NCT00599105
- Lead Sponsor
- University of California, Irvine
- Brief Summary
This study will investigate the association of angiogenesis in breast cancer measured by magnetic resonance imaging and biomarkers with long-term prognosis of patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 700
Inclusion Criteria
- Patient with a breast mass highly suspicious for malignancy from clinical, mammographic or sonographic examination.
- The study has been explained to the patient when she is scheduled for surgery.
- Healthy normal volunteers for imaging protocol optimization.
Exclusion Criteria
- Pregnancy
- Patients with implanted surgical clips (hemostatic clips) or other ferromagnetic material,
- Patients engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or who may have imbedded metal fragments from military activities,
- Patients with metallic implants, because they may cause artifacts in diagnostic images due to magnetic field distortion,
- Patients with implanted prosthetic heart valves,
- Patients with pacemakers, neuro-stimulation devices,
- A breast mass with features of benign tumor
- The patients unwilling to participate in the study or fail to sign the consent form
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method To investigate whether breast cancer with a higher angiogenesis activity is associated with a unfavorable outcome. 5 years from completion of enrollment
- Secondary Outcome Measures
Name Time Method To investigate whether angiogenesis of breast cancer is associated wit lymph node status at completion of enrollment
Trial Locations
- Locations (1)
Center for Functional Onco-Imaging, University of California
🇺🇸Irvine, California, United States