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Vitamin D and calcium and muscle strength

Phase 2
Completed
Registration Number
CTRI/2014/07/004711
Lead Sponsor
Indian Council of Medical Research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
228
Inclusion Criteria

1. Age between 18 years and 25 years.

2. Currently residing in Delhi with commitment for follow-up for 6 months.

3. Written consent for randomization and supplementation after they have gone through project information sheet.

4: Apparently healthy with no history of chronic illness at any time or acute illness during the preceding two months.

Exclusion Criteria

1. Subjects taking drugs which can affect bone mineral metabolism such as glucocorticoids, antitubercular, antiepileptics, levothyroxine, bisphosphonates, vitamin D and calcium supplementations

3. Those with history of any chronic renal or liver disorder or chronic diarrhea or any other chronic illness.

4. Subjects complaining of muscle aches and joint pain.

5. Serum total T4 and TSH suggestive of thyroid dysfunction.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in hand muscle grip strengthTimepoint: At six months of intervention
Secondary Outcome Measures
NameTimeMethod
Change in circulating testosterone with supplementation <br/ ><br>Timepoint: Baseline and at six months;Change in hand grip strength with change in circulating testosterone after six months of intervention with cholecalciferol with and without calcium supplementation <br/ ><br>Timepoint: Baseline and at six months;Correlation of hand grip, pinch grip and six minutes walk distance with circulating testosterone at baselineTimepoint: Baseline
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