NCT00842972已完成不适用
Is Carotid Intima-media Thickness Affected by A1C Variability?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
研究概览
简要总结
This study was conducted to evaluate the effect of A1C variability on the progression of carotid artery intima-media thickness in type 2 diabetic patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 34 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •fluoroscopy in carotid once a year during 2 years
排除标准
- •type 1 diabetes
- •history or clinical evidence of coronary artery disease or cerebral or peripheral vascular disease
- •the presence of albuminuria (defined as 24 hour urine albumin excretion ≥ 30 mg)
- •renal dysfunction (defined as creatinine blood level ≥ 2.0 mg/dL)
- •hepatic dysfunction (defined as alanine aminotransferase and/or aspartate aminotransferase blood level ≥ 3 × upper normal limit)
- •smoking within the past 3 months prior to commencement of the study
- •use of any medication likely to alter IMT such as calcium channel blocker, thiazolidinedione, antiplatelet agent (clopidogrel, cilostazol)
- •use of glucocorticoid
- •pregnancy
- •severe concomitant disease such as cancer
- •infection
- •Cushing's syndrome
- •acromegaly, or any other disorder likely to alter glycemia
- •primary hypercholesterolemia
- •hypothyroidism or hyperthyroidism
- •use of any hormonal drugs
- •alcoholism or drug abuse
研究者
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