Prediction of successful stroke rehabiliation outcome by functional connectivity
Recruiting
- Conditions
- I63.5Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
- Registration Number
- DRKS00014642
- Lead Sponsor
- Klinik für Neurologie Universität Jena
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
stroke in the previous 7 days resulting in motor deficits in the upper extremity
Exclusion Criteria
complete motor recovery during inpatient stay, limited understanding/ co-ability, previous cerebral ischemia, contraindications to MRI, unstable clinical situation
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation and thus prognosis prediction between short-term learning-associated functional connectivity changes in the motor cerebral system and the individual rehabilitation outcome.<br>The MRI, which is crucial for the prognosis, is performed during the stay in the acute hospital (days 4-7 after stroke). The change in functional connectivity is measured between 2 resting state measurements performed before and after a 12-minute sequence learning paradigm.<br>Motor outcome is the result of the Fugl-Meyer assessment scores after 6 months.<br>In short: Prediction of motor stroke outcome (Fugl Meyer score 6 months post stroke) of mean initally measured changes in functional connectivity induced by a 12 minute sequence learning paradigm.
- Secondary Outcome Measures
Name Time Method Association of the connectivity described in the primary endpoint with the following scores: RASP, NHPT, HADS, BSQ.