ESPRESSo: Enhancing spontaneous recovery of hand and arm movement with high intensity therapy beginning one week after stroke

Not Applicable

Recruiting

• Conditions: Stroke; Stroke - Ischaemic; Stroke - Haemorrhagic; Physical Medicine / Rehabilitation - Physiotherapy; Physical Medicine / Rehabilitation - Occupational therapy

• Registration Number: ACTRN12620000871943
• Lead Sponsor: The University of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-08-31
• Last Update Posted: 3 October 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

i.People with monohemispheric ischaemic stroke or intracerebral haemorrhage confirmed by CT or MRI admitted to Auckland City Hospital within the last 7 days
ii.First-ever stroke or previous stroke with no upper limb weakness
iii.At least 18 years old
iv.Received a Good” or Excellent” prediction from the Predict Recovery Potential (PREP2) algorithm
v.UE-FM score < 51 at enrolment
vi.Able to give informed consent
vii.Patients treated with intravenous thrombolysis and/or intra-arterial thrombectomy are eligible

Exclusion Criteria

i.UE-FM score > 50 at enrolment
ii.Cognition and/or communication impairment precluding informed consent or engagement with the research procedures, as determined by the patient’s clinical team
iii.Received a Limited” or Poor” PREP2 prediction
iv.Inability to sit in a chair and perform upper limb exercises
v.Life expectancy less than 12 months, as determined by the patient’s clinical team
vi.Upper limb motor performance limited by pre-existing conditions, such as musculoskeletal disease
vii.Residing out of region precluding in-person assessment
viii.Social and/or personal circumstances that interfere with the ability to return for therapy sessions and follow up assessments

Study & Design

• Study Type: Interventional
• Study Design: Not specified