COMPARISON OF RECOVERY OF FUNCTIONS AFTER STROKE IN PATIENTS WITH DIABETES MELLITUS AND WITHOUT DIABETES MELLITUS

Not Applicable

• Conditions: Health Condition 1: I60-I69- Cerebrovascular diseases

• Registration Number: CTRI/2021/05/033312
• Lead Sponsor: Renier Borges

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients between 18 and 85 years, admitted with first episode of cerebrovascular accident i.e. an abrupt onset of neurological deficit that is attributable to focal vascular cause, with neurological signs lasting for >24 hours 2. Patients with clinical and/or neuroimaging studies (CT/MRI brain) suggestive of cerebrovascular accident. FOR CASES1.Known cases of diabetes mellitus on treatment 2.Diabetes mellitus patients, diagnosed according to American Diabetes Association Criteria 2020.a) Fasting plasma glucose (FPG) >126 mg/dL (7.0 mmol/L). Fasting is defined as no caloric intake for at least 8 h Or b) 2-h plasma glucose >=200 mg/dL (11.1 mmol/L) after a 75 g oral glucose tolerance test

Or c) In a patient with classic symptoms of hyperglycemia or hyperglycemic crisis, a random plasma glucose >=200 mg/dL 11.1 mmol/L)

Or d) HbA1C >=6.5% (48 mmol/mol) FOR CONTROLS 1.No prior history of diabetes mellitus 2.No history of treatment with OHA or insulin for diabetes mellitus 3.HbA1c < 6.5

Exclusion Criteria

Exclusion criteria

1.Prior history of cerebrovascular accident

2.Movement disorder affecting limb movements including dystonia, athetosis, chorea and myoclonus.

3.Psychiatric illness interfering with activities of daily living or cognitive functions.

4.GCS < 8

5.Limb deformities

6.Impaired gait prior to stroke (musculoskeletal abnormalities or peripheral neuropathy)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1) To determine whether the presence of diabetes mellitus influences the functional recovery after stroke.Timepoint: Immediate, 2 weeks and 3 months.

Secondary Outcome Measures

Name	Time	Method
1) To administer modified Rankin scale and Functional independence measure scale to patients admitted with cerebrovascular accident on admission, at 2 weeks and at 3 months after cerebrovascular accident. <br/ ><br>2) To compare modified Rankin scale and Functional independence measure scale in patients with and without diabetes mellitus. <br/ ><br>3) To correlate HbA1c at admission with the modified Rankin scale and Functional independence measure scale at 3 months. <br/ ><br>Timepoint: immediate, 2 weeks and 3 months