Pulsed-dye laser as an adjuvant intervention to comedones treatment: A randomized controlled trial

Phase 3

Completed

• Conditions: Erythema index caused by comedone extraction after pulsed-dye laser treatment; pulsed-dye laser, comedone extraction, erythema, acne

• Registration Number: TCTR20190426001
• Lead Sponsor: Ratchadapiseksompotch Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-04-26
• Study Completion: 2020-02-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

1.healthy acne participants
2.aged between 12 and 25 years
3.mild to moderate acne severity according to the CASS (grade 2 and 3)
2.able to complete the study.

Exclusion Criteria

1.recent facial laser or light therapy within 3 months
2.use of systemic retinoids within 6 months
3.signs of androgen excess
4.current medication intakes
The washout periods to avoid external confounding effects were 2 weeks (topical acne treatments), 4 weeks (oral antibiotics), and 12 weeks (contraceptive medication).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Erythema due to comedone extraction 2 and 4 weeks after PDL Erythema index measured by mexameter

Secondary Outcome Measures

Name	Time	Method
acne severity (CASS), acne lesion counts and patients' satisfaction 2 and 4 weeks after PDL comprehensive acne severity scale, acne lesion counts and numeric rating scale, respectively