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Clinical Trials/NCT06706830
NCT06706830
Completed
Not Applicable

The Role of Lung and Diaphragm Ultrasonography in Predicting Clinical Progression in Patients Receiving High-Flow Nasal Oxygen and Non-Invasive Mechanical Ventilation Support for Hypoxemic Respiratory Failure

Simge Evren2 sites in 1 country91 target enrollmentJanuary 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diaphragm Ultrasonography
Sponsor
Simge Evren
Enrollment
91
Locations
2
Primary Endpoint
Lung and diaphragm ultrasound evaluation for risk of intubation
Status
Completed
Last Updated
last year

Overview

Brief Summary

The goal of this observational study is to evaluate whether the risk of intubation in patients with hypoxemic respiratory failure who were monitored in the intensive care unit and received non-invasive mechanical ventilation and high-flow nasal oxygen treatment could be predicted using lung and diaphragm ultrasound.

The main question it aims to answer is:

Can lung and diaphragm ultrasound predict the risk of intubation in patients with hypoxemic respiratory failure?

Detailed Description

Between January 1, 2024, and May 1, 2024, the diaphragm thickness fraction, excursion, LUS score, ROX index, and the LUSS/ROX index ratio were evaluated using lung and diaphragm ultrasound in 91 patients admitted to the intensive care unit with a diagnosis of hypoxemic respiratory failure. These evaluations were performed at the 6th, 12th, 24th, and 48th hours of their ICU stay, and during intubation if the decision for intubation was made

Registry
clinicaltrials.gov
Start Date
January 1, 2024
End Date
August 23, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Simge Evren
Responsible Party
Sponsor Investigator
Principal Investigator

Simge Evren

Principal Investigator

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Eligibility Criteria

Inclusion Criteria

  • PaO2 \<60 mmHg detected in arterial blood gas samples at the time of admission to the intensive care unit

Exclusion Criteria

  • Under the age of 18
  • History of lung and diaphragm surgery
  • Congenital, acquired or traumatic diaphragmatic hernia
  • Diaphragm paralysis
  • Hemodynamic instability requiring vasoactive drug support
  • Do not agree to participate in the study

Outcomes

Primary Outcomes

Lung and diaphragm ultrasound evaluation for risk of intubation

Time Frame: 48 hours

Lung and diaphragm ultrasound can predict risk of intubation

Secondary Outcomes

  • ROX index evaluation for risk of intubation(48 hours)
  • LUSS/ROX index ratio evaluation for risk of intubation(48 hours)

Study Sites (2)

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