Effects of resistance training on muscle strength and physical activity in frail older people

Not Applicable

Completed

• Conditions: Frailty in people aged over 70 years; Musculoskeletal Diseases; Sarcopenia

• Registration Number: ISRCTN10967873
• Lead Sponsor: Regional Research Council Vestlandet

Brief Summary

2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29988285 2020 results in https://pubmed.ncbi.nlm.nih.gov/32782626/ (added 14/08/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-23
• Study Completion: 2019-06-30
• Last Update Posted: 24 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 104

Inclusion Criteria

1. Aged >70 years
2. Living at home
3. Receiving home care due to functional and/or medical disabilities

Exclusion Criteria

1. Serious mental disorders and/or diagnoses/conditions that prevent testing or training

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Pilot study (10 weeks)<br> In the pilot study, the primary outcome was feasibility of performing the resistance training program with frail people.<br><br> Main trial (3 years): Outcomes were assessed every 6 months<br> The primary outcome was the ability to live self-reliantly and independently in their own home.<br>

Secondary Outcome Measures

Name	Time	Method
<br> Pilot study: The following measurements were taken at baseline and after the 10 weeks of intervention.<br> 1. Physical function assessed using time up and go, preferred and maximum walk speed, chair-raise and stair-climb)<br> 2. Muscle strength assessed by maximal isometric contraction and rate of force development in leg and arm)<br> 3. Daily physical activity measured by ActiGraph GT1M over a 5-day period.<br><br> Main trial: Endpoints were assessed every 6 months<br> 1. Physical function (time up and go, preferred and maximum walk speed, chair-raise and stair-climb)<br> 2. Muscle strength (maximal isometric contraction and rate of force development in leg and arm)<br> 3. Daily physical activity measured by ActiGraph GT1M over a 14-day period<br> 4. Quality of life using EQ-5D-5L questionnaire<br> 5. Fear of falling using Short FES I questionnaire<br>