Effectiveness of MST Versus ECT for Major Depressive Episode

Not Applicable

Recruiting

• Conditions: Major Depressive Disorder (MDD)

• Registration Number: NCT06409325
• Lead Sponsor: Shanghai Mental Health Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-5-7
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 210

Inclusion Criteria

Inclusion Criteria:<br><br> - Participants must meet the diagnostic criteria for MDD as outlined in the Diagnostic<br> and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).<br><br> - Participants must have a baseline score of 18 or higher on the 24-item Hamilton<br> Depression Rating Scale (HDRS-24).<br><br> - During the trial's treatment period, participants must be using a single<br> antidepressant medication at a stable dose.<br><br> - Participants must be between the ages of 18 and 65 years.<br><br> - Informed consent from both parents and legal guardians is required.<br><br>Exclusion Criteria:<br><br> - Individuals with current or history of organic brain disorders or neurological<br> disorders will be excluded from the study.<br><br> - Participants with a Wechsler Abbreviated Scale of Intelligence (WASI) score of less<br> than 70 will be excluded.<br><br> - Individuals currently taking antiepileptic drugs, benzodiazepines, or other<br> medications that may affect seizure activity will be excluded from the study.<br><br> - Those with exposure to ECT, modified ECT, MST, transcranial magnetic stimulation<br> (TMS), transcranial direct current stimulation (tDCS), transcranial alternating<br> current stimulation (tACS), or other neurostimulation treatments in last 6 months<br> will be excluded.<br><br> - Individuals with cochlear implants, cardiac pacemakers, implanted devices, or metal<br> in the brain will be excluded from participation.<br><br> - Pregnant or lactating individuals will be excluded from the study.<br><br> - Individuals currently participating in another concurrent clinical trial will not be<br> eligible for inclusion.<br><br> - Participants who refuse to provide informed consent to participate in the trial will<br> be excluded.<br><br> - Other circumstances deemed unsuitable for participation by researchers will result<br> in exclusion.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the response rate;the remission rate