NCT00492076已完成4 期
A Randomised, Double-Blind Placebo-Controlled Study Assessing the Short-Term Effect of a Dermatophagoides Pteronyssinus Extract, Quantified in Mass Units, in Subjects With Perennial Mite Induced Asthma
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Reduction in inhaled corticosteroids
研究概览
简要总结
The purpose of this study is to determine whether a short course of subcutaneous immunotherapy is efficacious in mite induced asthma. The efficacy is based on reduction in control medication.
详细描述
The control of mild-moderate persistent asthma include the need of concomitant medication, as inhaled corticosteroids. However, compliance in perennial asthma is low. The aim of this study is to assess the possibility to reduce the need of concomitant medication through a short-course of subcutaneous immunotherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 14 Years 至 55 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mild/moderate persistent asthma
- •Positive skin prick test or specific IgE to mites
- •Age: 14-55 years old
排除标准
- •Immunotherapy contraindications
- •Allergy to other inhalant allergens
- •Previous immunotherapy (5 years)with mites
结局指标
主要结局
Reduction in inhaled corticosteroids
时间窗: 4 months
次要结局
- Reduction in symptoms and rescue medication Tolerability(4 months)
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
3 期
Evaluation of Efficacy and Safety of Specific Immunotherapy With Modified Allergen Extracts of House Dust MitesAllergic RhinitisNCT01013116Roxall Medizin120
已完成
2 期
Subcutaneous Immunoglobulin Treatment of Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)Polyradiculoneuropathy, Chronic Inflammatory DemyelinatingNCT01017159University of Aarhus30
Unknown
3 期
A Multicenter Study to Evaluate Safety and Efficacy of Specific Immunotherapy With Modified Allergen ExtractsAllergic ConjunctivitisAllergic RhinitisNCT01012752Roxall Medizin150
已完成
2 期
Subcutaneous Immunoglobulin Treatment for Multifocal Motor NeuropathyMultifocal Motor NeuropathyNCT00268788University of Aarhus10
进行中（未招募）
3 期
Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical RemissionGiant Cell ArteritisNCT05380453Novartis Pharmaceuticals151