NL-OMON53264
Recruiting
Not Applicable
High Flow Nasal Oxygen For Hypercapnic, Acidotic Exacerbation Chronic Obstructive Pulmonary Disease. (HicaP) - HFNO in COPD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Franciscus Gasthuis & Vlietland
- Enrollment
- 40
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Known chronic obstructive pulmonary disease
- •Acute hypercapnic exacerbation of this condition, defined as:
- •o PaCO2\>45 mmHg or \>6\.0 kPa
- •o pH 7\.25\-7\.34
- •Age \>40 years
Exclusion Criteria
- •\- Metabolic (component of) acidosis, defined as a bicarbonate \<20 mmol/L.
- •\- Non\-invasive respiratory support (either NIV or HFNO) already started, e.g.
- •by ambulance or on the ward.
- •Immediate need for intubation, based on clinical judgement of the attending
- •Impossibility to apply either one of the two interventions
- •Patient not expected to give immediate or delayed informed consent (e.g.
- •cognitive impairment, psychological or mental inabilities).
- •Established home\-NIV or home CPAP, known indication for home\-NIV or CPAP
- •(e.g. OSAS or obesitas hypoventilation syndrome).
- •Impeding death
Outcomes
Primary Outcomes
Not specified
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