The prevention of Alzheimer's disease through regulation of amyloid beta synthesis and brake-down by propolis intake
Not Applicable
- Conditions
- type 2 diabetes dementia
- Registration Number
- JPRN-UMIN000015423
- Lead Sponsor
- Kyoto Prefectural University of Medicine, Graduate School of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients who did not agree with this study 2) Patients with severe renal dysfunction and severe hepatic dysfunction 3) Type 1 diabetes and other specific types of diabetes resulting from specific genetic syndromes, surgery, drugs, malnutrition, infections, and other illnesses 4) Patients treated with insulin 5) Patients with dementia or neurodegenerating disease 6) Patients who is taking drugs which affect the cognitive function 7) Patients who changed oral hypoglycemic drugs significantly 8) Patients who changed drugs which affect pH of interstitial fluid 9) Patients judged by the investigator to be ineligible for some other reason
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method amyloid-beta, Tau protein, activity of the beta-amyloid converting enzyme 1
- Secondary Outcome Measures
Name Time Method HbA1c, fasting plasma glucose, serum insulin, Mini-Mental State Examination