Excavation of onset risk of Alzheimer's disease
Not Applicable
- Conditions
- Mild cognitive impairment (MCI) Healthy adult volunteers
- Registration Number
- JPRN-UMIN000017442
- Lead Sponsor
- Department of Neurology Oita University Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 1091
Inclusion Criteria
Not provided
Exclusion Criteria
Any significant neurologic or psychiatric disease other than MCI (1). History of significant head trauma, alcohol or substance abuse (2,6,7). Any significant systemic illness or unstable medical condition which could lead to difficulty complying with the protocol : diabetes mellitus, thyroid disease, anemia, cardiac disease, or hypertension (3,4,5,10,11). Clinically significant and severe abnormalities in hepatic and/or renal function (8,9). Subjects who participate in another study within 3 months (12). Subjects who donated blood (over 200ml or over 400ml, within 1 month or 3 months, respectively (13). Subjects who are judged to be inadequate for their eligibility by investigators (14).
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identification of non-genetic risk factors for onset of AD via analysis of differences between MCI individuals that convert to AD and MCI nonconverters (who have been scanned using PET)
- Secondary Outcome Measures
Name Time Method Group differences for each imaging and biomarker measurement.