Physiopathological and Therapeutic Value of microRNA in the Progression of Carotid Artery Plaques: Carotid Protocol and microRNA

• Conditions: Carotid Arteries

• Registration Number: NCT02804659
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Molecular analysis of the atheroma plaque. Screening for a novel biomarker of carotid status.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07
• Study First Submitted: 2016-06-15
• Study First Submitted QC: 2016-06-16
• Study First Posted: 2016-06-17
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-09
• Last Update Posted: 2018-08-10
• Primary Completion: 2019-03
• Study Completion: 2019-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Adults having to undergo carotid thromboendarteriectomy
• social security coverage
• provision of study information
• consent to participation.

Exclusion Criteria

• Previous carotid artery surgery
• refusal to participate in the study
• or inability to give consent.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
expression level of the seven miRNAs of interest	Day of surgery	expression level of the seven miRNAs of interest in the serum and in carotid artery plaques : miR-100, miR-125a, miR-127, miR-133a, miR-145, miR-221

Trial Locations

Locations (1)

CHU Amiens; 🇫🇷 Amiens, France