JPRN-UMIN000031866已完成未知
An exploratory study to identify biomarkers of resistance to chemotherapy in multiple myeloma - biomarker study in MM
The Institute of Medical Science, The University of Tokyo0 个研究点目标入组 14 人开始时间: 2018年3月23日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 14
研究概览
简要总结
Results: We identified several driver mutations by combined analysis of next-generation sequencing and existing databases of candidate oncogenes. Furthermore, relapse was detected more sensitively by monitoring the circulating cfDNA with these driver mutations than by conventional serum free-light chain examination. Conclusion: These results suggest the potential utility of cfDNA in the PB plasma of patients as a relevant early biomarker for MM relapse.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Patients who are found to be inappropriate for this trial as judged by the principal investigator or the sub-investigator
研究者
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