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Clinical Trials/CTRI/2017/02/007864
CTRI/2017/02/007864
Completed
未知

Thromboelastography guided blood product transfusion in cirrhosis patients with acute variceal bleeding: a Randomized Controlled Trial - TEGVAR

Department of Gastroenterology AIIMS New Delhi0 sites60 target enrollmentTBD
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ConditionsHealth Condition 1: null- Cirrhosis with Variceal bleeding

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: null- Cirrhosis with Variceal bleeding
Sponsor
Department of Gastroenterology AIIMS New Delhi
Enrollment
60
Status
Completed
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
December 29, 2017
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
Department of Gastroenterology AIIMS New Delhi

Eligibility Criteria

Inclusion Criteria

  • •1\.Cirrhosis with acute variceal bleeding
  • •2\.Age between 18\-65 years
  • •3\.Willing to participate in the study

Exclusion Criteria

  • •1\.Variceal bleeding secondary to causes other than cirrhosis. eg, extrahepatic venous obstruction, hepatic venous outflow track obstruction
  • •2\.Patients with malignancy/disseminated intravascular coagulation (DIC)/known coagulopathic disorder (haemophilia) apart from cirrhosis.
  • •3\.History of intake of platelets inhibitors (eg, aspirin, clopidogrel) and drugs affecting coagulation cascade (eg, vitamin K anatagonists) within past 7 days
  • •4\.Pregnant women and those on oral contraceptives
  • •5\.Patients with chronic renal failure
  • •6\.History of underlying hypercoagulable/ hypocoagulable states eg. paroxysmal nocturnal hemoglobunuria (PNH), polycythemia vera etc
  • •7\.Patients receiving blood products (fresh frozen plasma and platelet prior to thromboelastography)
  • •8\.Patients with shock
  • •10\.Acute on chronic liver failure
  • •11\.Hepatorenal syndrome

Outcomes

Primary Outcomes

Not specified

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