Improvement of nutritional state by intradialytical parenteral nutrition in children treated with haemodialysis
Completed
- Conditions
- Nutritional, Metabolic, EndocrineMalnutrition/Haemodialysis pediatric patients
- Registration Number
- ISRCTN59440030
- Lead Sponsor
- Baxter Healthcare Corporation (USA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Patients aged 6-17 years
2. Anthropometry-BIA nutrition (ABN) Score <10.33
3. Functional haemodialysis vascular access
4. Expected time in haemodialysis at least 6 months
5. No evidence of active infection
6. Informed consent/assent properly signed
Exclusion Criteria
1. Hepatic dysfunction
2. Congenital anomalies in amino acid metabolism
3. Use of immunosuppressive drugs
4. Treatment with growth hormone
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in ABN score (anthropometry-bioimpedance analysis-nutrition) at 3 and 6 months
- Secondary Outcome Measures
Name Time Method 1. improvement in inflammation biomarkers (IL-6, TNF alpha)<br>1. Peripheral blood gene expression of IL6, TNF alpha, IFN gamma, 18s-rRNA at baseline, 3 and 6 months<br>2. Adverse events to nutritional intervention