Histological remission in ulcerative colitis: comparing histological activity indexes
Completed
- Conditions
- lcerative colitisDigestive SystemUlcerative colitis
- Registration Number
- ISRCTN61139227
- Lead Sponsor
- Radboud University Medical Center (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
1. A colonoscopic examination between January 2014 and July 2015
2. A well-established diagnosis of UC according to clinical and histological criteria
3. Endoscopic mucosal healing throughout the entire colon according to Mayo (=1)
4. Randomly taken colonic biopsy specimens in both left and right colon with a clear description of the microscopic features by the pathologist
Exclusion Criteria
1. Mayo endoscopic score > 1
2. Diagnosed with either Crohn’s disease or indeterminate colitis
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intra- and inter-observer variability all histological indices
- Secondary Outcome Measures
Name Time Method The relationship with endoscopic mucosal healing, and the relationship between the initial judgment of the primary pathologist in all scoring systems