Exercise in Autoimmune Myasthenia Gravis and Myasthenic Syndromes

Completed

• Conditions: Autoimmune Myasthenia Gravis; Congenital Myasthenic Syndrome; Myasthenia Gravis; Lambert-Eaton Myasthenic Syndrome

• Registration Number: NCT05408702
• Lead Sponsor: Institut de Myologie, France

Brief Summary

A few recent observational studies show that despite the lack of clear recommendations, many individuals with myasthenia participate in exercise. However, no link has been found between exercise and the severity of myasthenia symptoms, measured by the Muscle Myasthenia Score or the Myasthenia Gravis Composite Score. This suggests that there are other factors that may limit or prevent some individuals from being active, or factors which may facilitate participation in exercise.

Studies in other diseases have shown that there are internal (beliefs, motivation, etc.) and external (cost, accessibility, etc.) factors unrelated to the disease which may play a role in exercise participation.

The aim of this study is to identify factors that facilitate or limit exercise in individuals with autoimmune myasthenia gravis, congenital myasthenia syndrome and Lambert-Eaton syndrome.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-12
• Primary Completion: 2022-05-15
• Study Completion: 2022-05-15
• Study First Submitted: 2022-05-31
• Status Verified: 2022-06
• Study First Submitted QC: 2022-06-03
• Last Update Submitted: 2022-06-03
• Study First Posted: 2022-06-07
• Last Update Posted: 2022-06-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• at least 18 years old
• confirmed diagnosis of MG or SMC or LEMS
• Live in France or its territories
• Provide consent

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Barriers and facilitators to exercise	Six months

Trial Locations

Locations (1)

Online Questionnaire; 🇫🇷 Paris, France