Serious Game to Teach Opioid Overdose Response

Phase 2

Not yet recruiting

• Conditions: Opioid Overdose

• Registration Number: NCT06727786
• Lead Sponsor: University of Nevada, Reno

Brief Summary

This study evaluates the efficacy of a serious game to teach students how to recognize and respond to opioid overdose

Detailed Description

This study uses an interactive realistic film depicting an opioid overdose to teach high school/middle school students how to recognize and respond to opioid overdose. The film features a person who finds their friend unresponsive, with evidence of opioid use. The unresponsive friend demonstrates signs of opioid overdose. The hero must recognize opioid overdose, administer naloxone (opioid antedote) and perform CPR. The film is made interactive by the narrator pausing the action of the film, and asking learners to answer questions/make choices.

Efficacy is tested on the day of training, and 2-4 months later. Efficacy is measured by student ability to correctly administer naloxone to a manikin, perform CPR, and answer knowledge questions about opioid overdose. Other studied metrics include student engagement/enjoyment, attitudes/biases, and emotions created by the training. These will be tested through validated questionnaires.

Study Timeline

• Status Verified: 2024-12
• Study First Submitted: 2024-12-03
• Study First Submitted QC: 2024-12-05
• Last Update Submitted: 2024-12-05
• Study First Posted: 2024-12-11
• Last Update Posted: 2024-12-11
• Study Start: 2026-02-01
• Primary Completion: 2026-12-01
• Study Completion: 2027-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 850

Inclusion Criteria

• Student at participating school, enrolled in Health or Science Class

Exclusion Criteria

• None

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Naloxone administration Skill	Day of training, and 2-3 months	Properly administer naloxone to a victim of opioid overdose Study personnel will ask students to administer naloxone to a CPR manikin. Personnel will use a checklist from the Center for Addiction and Mental Health to score student responses.

Secondary Outcome Measures

Name	Time	Method
CPR Skill	Day of training, and 2-3 months	Ability to perform high-quality CPR Students will be asked to perform CPR on a CPR manikin for 2 minutes. CPR skill will be measured with the CPR Meter 2 from Laerdal, which reports compression rate, depth, and percent recoil. We will consider "high quality CPR" students who perform 70% or more of compressions at appropriate rate (100-120/min), depth (2-2.5inches), and full recoil.
Attitudes towards opioid overdose	Day of training, and 2-3 months	Attitudes, enjoyment, and emotions towards opioid overdose; Emotions will be measured using the PANAS scale (Positive And Negative Affect Scale) which consists of 10 positive and 10 negative emotion words. The total score is calculated by finding the sum of the 10 positive items, and then the 10 negative items. Scores range from 10 - 50 for both sets of items. For the total positive score, a higher score indicates more of a positive affect.; Engagement and enjoyment will be measured using Likert-style questions asking for agreement with statements such as "I enjoyed CPR training," "CPR training was fun," "I will use CPR training in the future," "It is important to learn CPR"; Attitudes will be measured with a custom questionnaire asking Likert-style responses to statements regarding opioid overdose.
Knowledge of opioid overdose response	Day of training, and 2-3 months	Knowledge of how to recognize and respond to opioid overdose A questionnaire of custom-created multiple choice questions will assess student knowledge of how to recognize and respond to opioid overdose.